Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viral Recombination00:57

Viral Recombination

25.2K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
25.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
CRISPR and crRNAs02:53

CRISPR and crRNAs

19.2K
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...
19.2K
Predator-Prey Interactions02:39

Predator-Prey Interactions

21.7K
Predators consume prey for energy. Predators that acquire prey and prey that avoid predation both increase their chances of survival and reproduction (i.e., fitness). Routine predator-prey interactions elicit mutual adaptations that improve predator offenses, such as claws, teeth, and speed, as well as prey defenses, including crypsis, aposematism, and mimicry. Thus, predator-prey interactions resemble an evolutionary arms race.
21.7K
The Colonization of Land02:22

The Colonization of Land

37.8K
Changes in the environment of the early Earth drove the evolution of organisms. As prokaryotic organisms in the oceans began to photosynthesize, they produced oxygen. Eventually, oxygen saturated the oceans and entered the air, resulting in an increase in atmospheric oxygen concentration, known as the oxygen revolution approximately 2.3 billion years ago. Therefore, organisms that could use oxygen for cellular respiration had an advantage. More than 1.5 years ago, eukaryotic cells and...
37.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient ratings in exercise therapy for the management of tendinopathy: a systematic review with meta-analysis.

Physiotherapy·2023
Same author

Identification of proteins associated with development of metastasis from cutaneous squamous cell carcinomas (cSCCs) via proteomic analysis of primary cSCCs.

The British journal of dermatology·2020
Same author

Perspectives and attitudes of pediatricians concerning post-discharge care practice of premature infants.

Journal of neonatal-perinatal medicine·2017
Same author

Issues of intimacy and sexual dysfunction following major head and neck cancer treatment.

Oral oncology·2009
Same author

Radial artery as a conduit for diabetic crural bypass.

The British journal of surgery·2003
Same author

Cervical length and funneling at 23 weeks of gestation in the prediction of spontaneous early preterm delivery.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2001

Related Experiment Video

Updated: Feb 14, 2026

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
05:48

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice

Published on: September 26, 2019

9.9K

Congenital segmental emphysema: an evolving lesion.

S Paramalingam1, E Parkinson, M Sellars

  • 1King's College Hospital, Paediatric Surgery, London, United Kingdom.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|April 17, 2010
PubMed
Summary

Congenital segmental emphysema (CSE) shows postnatal evolution from solid to hyperinflated lung segments. This condition, often misdiagnosed as CCAM, may involve bronchial atresia and air trapping.

More Related Videos

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

49.5K
Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 17, 2014

25.2K

Related Experiment Videos

Last Updated: Feb 14, 2026

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
05:48

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice

Published on: September 26, 2019

9.9K
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

49.5K
Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 17, 2014

25.2K

Area of Science:

  • Pediatric Pulmonology
  • Thoracic Surgery
  • Radiology

Background:

  • Congenital segmental emphysema (CSE) is a recently identified congenital parenchymal lung anomaly.
  • It presents antenatally and evolves postnatally from a solid to a hyperinflated segment.

Purpose of the Study:

  • To characterize the features and clinical course of congenital segmental emphysema (CSE).
  • To differentiate CSE from congenital cystic adenomatoid malformation (CCAM).

Main Methods:

  • Retrospective review of a single-center tertiary referral database (Jan 1994 - Dec 2007).
  • Analysis of antenatal imaging, postnatal CT scans, surgical findings, and histology.

Main Results:

  • 12 out of 130 infants with antenatal lung anomalies were diagnosed with CSE.
  • Antenatal imaging showed microcystic or hyperechogenic lesions.
  • Postnatal CT revealed evolution to segmental hyperlucency, sometimes with a bronchocele.
  • Surgical specimens confirmed hyperinflated segments, with histology showing dilated alveolar spaces.

Conclusions:

  • CSE is part of the spectrum of CCAM and sequestration, with distinct postnatal evolution.
  • Volume changes in CSE may precede symptoms and are potentially linked to segmental bronchial atresia and air trapping.