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Updated: Jun 13, 2026
06:12
Quasi-metagenomic Analysis of Salmonella from Food and Environmental Samples
Published on: October 25, 2018
Salmonella enterica bacteraemia: a multi-national population-based cohort study
Kevin B Laupland1, Henrik C Schønheyder, Karina J Kennedy
1Department of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada. kevin.laupland@calgaryhealthregion.ca
BMC Infectious Diseases
|April 20, 2010
Summary
Salmonella enterica bacteremia is an emerging global threat. This study defined its occurrence and risk factors across international populations, revealing significant regional variations.
Area of Science:
- Infectious Diseases
- Epidemiology
- Microbiology
Background:
- Salmonella enterica is a significant and growing cause of invasive infections globally.
- Limited population-based data exist on the incidence and epidemiology of S. enterica bacteremia.
- Understanding regional and temporal patterns is crucial for public health interventions.
Purpose of the Study:
- To determine the incidence of Salmonella enterica bacteremia in a large international population.
- To evaluate temporal trends and regional differences in S. enterica bacteremia.
- To identify risk factors associated with typhoidal and non-typhoidal Salmonella bacteremia.
Main Methods:
- Population-based laboratory surveillance was conducted in six regions across Finland, Australia, Denmark, and Canada.
- Data were collected over an eight-year period (2000-2007) covering approximately 7.7 million residents.
- Incidence rates, serotype distribution, and risk factors were analyzed.
Main Results:
- A total of 622 Salmonella enterica bacteremia cases were identified, with an annual incidence of 1.02 per 100,000 population.
- Typhoidal Salmonella bacteremia incidence was 0.21/100,000/year, while non-typhoidal bacteremia incidence was 0.81/100,000/year.
- Significant regional variability was observed, with increasing non-typhoidal cases in later years. Advancing age and male gender were risk factors for non-typhoidal disease, while typhoidal disease decreased with age.
Conclusions:
- Salmonella enterica bacteremia represents an important emerging infectious disease with considerable international variation.
- Regional factors significantly influence the risk of Salmonella enterica bacteremia.
- Further investigation into these regional determinants is warranted to inform targeted control strategies.
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