Related Experiment Video
Updated: Jun 13, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
A case-control study of sex differences in strategic processing and episodic memory in obsessive-compulsive disorder
Cinto Segalàs1, Pino Alonso, Javier Labad
1Department of Psychiatry, Obsessive-Compulsive Disorder Clinical and Research Unit, Hospital Universitario de Bellvitge, Barcelona 08907, Spain. csegalas@bellvitgehospital.cat
Abstract:
Although clinical and genetic data for obsessive-compulsive disorder (OCD) support the hypothesis of sexual dimorphism, the neuropsychological findings remain inconclusive. The aim of our study was to determine whether there are differences in cognitive performance between men and women with OCD as compared with healthy controls (HCs). A neuropsychological battery was administered to 50 patients with OCD (31 men and 19 women) and 50 HCs matched by sex, age, and educational level with patients. We evaluated intelligence, attention, episodic memory, and use of organizational strategies during encoding of verbal and nonverbal information. Male patients scored worse than controls did in measures of nonverbal memory tasks, whereas the cognitive performance of women with OCD was consistent with that of their HC counterparts. These results suggest a distinct pattern of cognitive dysfunction specific to the patients' sex.
Related Concept Videos
Obsessive-Compulsive Disorder
Personality Disorders: Dependent and Obsessive-Compulsive
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Case Studies
Sex Linked Disorders
Panic Disorder
Role of Cerebellum and Prefrontal Cortex in Memory

