Related Experiment Video
Updated: Jun 13, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Temperamentsxgenes in bipolar I and bipolar II disorder patients
Ching-I Lin1, Sheng-Yu Lee, Yun-Hsuan Chang
1Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.
Abstract:
We found the main effects of harm avoidance temperament in predicting bipolar I and II, but the interaction between novelty seeking and Ser9Gly polymorphisms of dopamine D3 receptor gene was demonstrated in bipolar-I patients only. This study provided evidence that differences existed between BP-I and BPII in gene and temperament interactions.
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