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Radiological Investigation II: MRI and Ventilation Perfusion Scan

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Related Experiment Video

Updated: Jun 13, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Evaluation of solid lesions affecting masticator space with diffusion-weighted MR imaging.

Pingzhong Wang1, Jie Yang, Qiang Yu

  • 1Department of Radiology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
|April 20, 2010
PubMed
Summary
This summary is machine-generated.

Diffusion-weighted MRI helps distinguish benign from malignant masticator space lesions. However, it cannot reliably differentiate inflammatory conditions from most cancers, except for osteosarcomas.

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Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Masticator space lesions present diagnostic challenges.
  • Accurate differentiation is crucial for appropriate treatment planning.

Purpose of the Study:

  • To assess the utility of diffusion-weighted magnetic resonance (MR) imaging in differentiating solid lesions within the masticator space.
  • To evaluate the diagnostic performance of apparent diffusion coefficients (ADCs) in classifying lesion types.

Main Methods:

  • Diffusion-weighted echo-planar MR imaging was performed on 78 subjects with masticator space lesions.
  • Lesions were pathologically classified into benign tumors (Group 1), inflammatory diseases (Group 2), and malignant tumors (Group 3).
  • Mean ADCs were calculated and statistically compared among groups using Kruskal-Wallis and Mann-Whitney U tests.

Main Results:

  • Significant differences in ADCs were observed among the three groups (P = .0001).
  • Benign lesions (Group 1) showed higher ADCs compared to malignant tumors (Group 3) and inflammatory diseases (Group 2).
  • No significant ADC difference was found between inflammatory diseases (Group 2) and most malignant tumors (Group 3), except for osteosarcomas.

Conclusions:

  • Diffusion-weighted MR imaging is valuable for differentiating benign solid lesions from malignant tumors in the masticator space.
  • Inflammatory lesions are difficult to distinguish from most malignant tumors, with osteosarcomas being a notable exception.