[Bacteremia in febrile children]

T Y Lin1

  • 1Department of Pediatrics, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.

Changgeng Yi Xue Za Zhi
|March 1, 1991
PubMed

Insights

Bacteremia in febrile children under two is uncommon, with a 2% incidence in this study. Neither white blood cell count nor temperature reliably predicted bacteremia in young patients.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Context:

  • Bacteremia in young children with fever is a concern due to potential serious complications like meningitis.
  • Previous research suggests a low incidence but significant risk in specific pediatric populations.
  • The study focuses on febrile children presenting to an emergency department without apparent serious illness or viral infection.

Purpose:

  • To determine the incidence of bacteremia in febrile children aged under 15 in the Taipei area.
  • To evaluate the predictive value of white blood cell (WBC) count and body temperature for bacteremia in this population.
  • To identify common pathogens causing bacteremia in different pediatric age groups.

Summary:

  • A study of 300 febrile children (body temperature >= 39°C) in Taipei found an overall bacteremia incidence of 2% (6/300).
  • Incidence was highest in neonates (13%) and infants aged 1 month to 1 year (5%), with pathogens including Group D Streptococcus, Streptococcus viridans, Escherichia coli, and Salmonella species.
  • Neither elevated white blood cell count nor high body temperature demonstrated predictive value for bacteremia in the studied children.

Impact:

  • This research highlights the low incidence of bacteremia in febrile children who appear well, challenging the utility of routine WBC counts and temperature for prediction.
  • Findings suggest that clinical assessment may be more crucial than simple laboratory markers in identifying bacteremia risk in this age group.
  • The study provides valuable epidemiological data on bacteremia pathogens in Taiwanese children, aiding in targeted treatment strategies.

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...