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Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain
Published on: August 30, 2022
Quebec Back Pain Disability Scale was responsive and showed reasonable interpretability after a multidisciplinary
Christophe Demoulin1, Raymond Ostelo, J André Knottnerus
1School of Public Health and Primary Care Research, Maastricht University, Maastricht, The Netherlands. christophe.demoulin@ulg.ac.be
Objective:
To investigate responsiveness and interpretability of the Quebec Back Pain Disability Scale.
Study Design And Setting:
The Quebec Back Pain Disability Scale was administered twice (pretreatment: T1; and posttreatment: T2) to 212 patients with chronic low back pain. Analyses were based on the general perceived effect scale score and Quebec Back Pain Disability Scale score changes between T1 and T2.
Results:
The smallest detectable change reached 15.8 points, whereas the optimal cutoff value was found to be 5 points, with area under the curve=0.850 (95% confidence interval: 0.786-0.914), sensitivity=78%, and specificity=77%. A complementary analysis of the receiver operating characteristics based on the Quebec Back Pain Disability Scale score change expressed in percentage revealed an optimal cutoff point of 18.1% (area under the curve=0.856, sensitivity=72%, and specificity=85%). Quebec Back Pain Disability Scale baseline scores and the way they are used to cluster patients influenced the optimal cutoff point.
Conclusions:
This study proposes values for responsiveness and interpretability indicators for patients with chronic low back pain referred for multidisciplinary treatment. The baseline score and the way to cluster patients with regard to this score have to be taken into account while interpreting the score change after treatment.
