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Related Experiment Video

Updated: Jun 13, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Published on: August 11, 2023

Oral cancer: clinical features.

Jose Bagan¹, Gracia Sarrion, Yolanda Jimenez

¹Valencia University, Department of Stomatology, University General Hospital, Valencia, Spain. bagan@uv.es

|April 20, 2010

Summary

Oral squamous cell carcinoma (OSCC), a common oral cancer, presents with pain and distinct lesions. Early detection is key for differentiating OSCC from other oral malignancies.

Area of Science:

Oncology
Oral Pathology

Background:

Oral squamous cell carcinoma (OSCC) represents over 90% of oral malignancies.
Understanding OSCC clinical characteristics and differential diagnosis is crucial for patient outcomes.

Purpose of the Study:

To review the clinical presentation of oral squamous cell carcinoma.
To outline the differential diagnosis for OSCC.

Main Methods:

Literature review of clinical characteristics of OSCC.
Comparative analysis of OSCC with other oral malignant diseases.

Main Results:

Pain is the most frequent presenting symptom of OSCC.
The tongue and floor of the mouth are common sites for OSCC.
Early OSCC may appear as asymptomatic erythroleukoplastic areas; advanced stages present as ulcers or rigid lumps with irregular margins.

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Last Updated: Jun 13, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

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Published on: August 11, 2023

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Conclusions:

Accurate differential diagnosis of OSCC is essential, distinguishing it from rapidly growing malignancies like lymphomas, sarcomas, and metastases.