Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...

Disturbances in Heart Rhythm

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A double endocrine-disrupting effect of PFAS on intra- and extra-thyroid targets: inhibition of iodide uptake and interference with MCT8-mediated T3 transport in vitro.

Environmental pollution (Barking, Essex : 1987)·2026

Same author

" Real-world procedural outcomes on adoption of a novel stylet-driven, fixed-helix lead for left bundle branch area pacing: Insights from the Conduction-System pacing Italian Network Group (C-SING)".

Heart rhythm·2026

Same author

Modulation of chemokine secretion and oxidative stress <i>in vitro</i> in thyroid cells after exposure to thiocyanate, nitrate, or perchlorate.

Frontiers in endocrinology·2026

Same author

Impact of Left Bundle Branch Area Pacing on Echocardiographic Parameters and Symptoms: Data From the Conduction System Pacing Italian Network Group (C-SING) Study.

Journal of cardiovascular electrophysiology·2026

Same author

Early electrocardiographic diagnosis of ST-segment elevation myocardial infarction during cardiac resynchronization via left bundle branch area pacing.

European heart journal. Case reports·2026

Same author

Studying endocrine disrupting chemicals from molecular targets to mixture model approach: lessons from the thyroid model.

The Journal of clinical endocrinology and metabolism·2026

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

Atrial asynchrony and function before and after electrical cardioversion for persistent atrial fibrillation.

Gabriele Dell'Era¹, Elisa Rondano, Elena Franchi

¹Cardiology Clinic, Eastern Piedmont University, Azienda Ospedaliera Universitaria Maggiore della Carità, Novara, Italy.

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology

|April 20, 2010

Summary

Restoring sinus rhythm (SR) after atrial fibrillation (AF) improves left atrial (LA) mechanical function and endocrine profile. LA mechanical data before cardioversion can predict AF recurrence.

More Related Videos

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Related Experiment Videos

Last Updated: Jun 13, 2026

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Area of Science:

Cardiology
Echocardiography
Atrial Electrophysiology

Background:

The relationship between left atrial (LA) electrical and mechanical activity is complex.
Echocardiographic strain analysis offers non-invasive assessment of LA mechanical synchrony and function.
Understanding LA mechanical changes post-cardioversion (CV) is crucial for managing atrial fibrillation (AF).

Purpose of the Study:

To evaluate how novel strain analysis tools describe improvements in LA mechanical function after restoring sinus rhythm (SR) via electrical CV.
To investigate the correlation between enhanced LA mechanical function and changes in endocrine profile.
To determine if pre-CV LA mechanical data can predict AF recurrence.

Main Methods:

Seventy-three patients with persistent AF underwent transthoracic echocardiography before and 1 month after successful electrical CV.
Speckle-tracking 2D-strain and asynchrony (TP-SD) were assessed, alongside traditional echocardiographic parameters (MR, LA volume, LV function, diastolic parameters).
Plasmatic brain natriuretic peptide (BNP) levels were measured before and after CV.

Main Results:

Successful CV significantly reduced LA asynchrony (TP-SD) and LA volume, while increasing LA deformation (peak strain) and LV ejection fraction.
Brain natriuretic peptide (BNP) levels decreased by one-third post-CV.
The TP-SD/peak strain ratio demonstrated a significant capacity to predict AF recurrence at 1-year follow-up.

Conclusions:

The novel non-invasive approach effectively describes LA mechanical behavior changes during AF and its improvement after SR restoration.
LA mechanical improvements are associated with favorable endocrine profile changes.
Pre-CV LA mechanical data, specifically the TP-SD/peak strain ratio, can predict long-term AF recurrence.