Related Experiment Video
Updated: Jun 13, 2026

A Simplified Model for Heterotopic Heart Valve Transplantation in Rodents
Published on: September 21, 2021
Somatic growth after corrective surgery for congenital heart disease
Kürşad Tokel1, Emine Azak, Canan Ayabakan
1Department of Pediatrics, Başkent University Faculty of Medicine, Ankara, Turkey.
Insights
Somatic growth in infants post-congenital heart surgery is mainly influenced by preoperative malnutrition and socioeconomic factors, not heart defect severity. Adequate nutrition and early surgery support optimal catch-up growth.
Area of Science:
- Pediatric Cardiology
- Growth and Development
- Congenital Heart Disease
Background:
- Congenital heart disease (CHD) significantly impacts infant somatic growth.
- Post-surgical recovery and long-term growth trajectories require detailed investigation.
Purpose of the Study:
- To evaluate somatic growth patterns in infants following corrective surgery for CHD.
- To identify factors influencing postoperative catch-up growth and anthropometric outcomes.
Main Methods:
- Prospective study of 60 infants undergoing corrective CHD surgery, categorized into four groups based on clinical presentation.
- Anthropometric measurements (weight, length, head circumference z-scores) collected preoperatively and up to 12 months post-surgery.
- Analysis of dietary intake, socioeconomic status, and perioperative factors.
Main Results:
- 85% of infants presented with malnutrition; family income, diet, and preoperative malnutrition significantly affected postoperative weight (p < 0.05).
- Heart defect severity did not significantly influence postoperative anthropometric measurements (p > 0.05).
- Seven patients failed to reach a z-score > -1 by 12 months, primarily in groups with severe defects or cyanosis without pulmonary hypertension.
Conclusions:
- Catch-up growth predominantly occurs within the first year after corrective surgery.
- Preoperative chronic malnutrition delays growth recovery, highlighting the importance of nutritional support.
- Optimizing caloric intake and performing early corrective surgery can help fulfill normal growth potential in these children.
Abstract:
We report the somatic growth characteristics of 60 infants who underwent corrective surgery for congenital heart disease. Patients were assigned to the following groups: Group 1, cyanosis with pulmonary hypertension (PH); Group 2, cyanosis without PH; Group 3, large left-to-right shunt and PH; and Group 4, left-to-right shunt or obstructive heart lesion and no PH. Weight, length, and head circumference measurements and z scores were obtained before the operation, at 45 days, and 3, 6, and 12 months after the operation. Details about dietary intake, socioeconomic status at presentation, length of stay in the intensive care unit, hospitalization period, and perioperative events were noted. The endpoint was reaching a z score > -1 for all anthropometric measurements. At presentation, 51 patients (85%) had malnutrition. The family income, dietary intake, and presence of preoperative chronic malnutrition were interrelated and influenced the weight of the patient at all times during the postoperative follow-up (p < 0.05 for all values). The severity of the heart defect had no significant influence on the postoperative anthropometric measurements (p > 0.05). The lowest preoperative z scores for weight and height were observed in Group 3. Seven patients could not achieve the endpoint at the end of 12 months (4 in Group 3 and 3 in Group 2). Catch-up growth is attained mostly in the first year after corrective surgery. Delays in reaching z scores > -1 are observed in the chronically malnourished children. If adequate calories are provided and early corrective surgery is performed, the normal growth potential may be fulfilled.
Related Concept Videos
Cellular Adaptation II: Hypertrophy
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Cellular Adaptation III: Hyperplasia
Growth of Cartilage and Bone Tissue

