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Updated: Jun 13, 2026
A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
Published on: March 23, 2018
Relative adrenal insufficiency and hemodynamic status in cardiopulmonary bypass surgery patients. A prospective
José L Iribarren1, Juan J Jiménez, Domingo Hernández
1Critical Care Department, Hospital Universitario de Canarias, Ofra s/n, La Cuesta, 38320 La Laguna, Tenerife, España. joseluis.iribarren@gmail.com
Background:
The objectives of this study were to determine the risk factors for relative adrenal insufficiency in cardiopulmonary bypass patients and the impact on postoperative vasopressor requirements.
Methods:
Prospective cohort study on cardiopulmonary bypass patients who received etomidate or not during anesthetic induction. Relative adrenal insufficiency was defined as a rise in serum cortisol
Results:
120 elective cardiopulmonary bypass patients were included. Relative adrenal insufficiency (Deltacortisol
Conclusions:
Relative adrenal insufficiency in elective cardiopulmonary bypass patients may induce postoperative vasopressor dependency. Use of etomidate in these patients is a modifiable risk factor for the development of relative adrenal insufficiency that should be avoided.
