Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...

Pulmonary Function Tests

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

Factors Affecting Pulmonary Ventilation

Factors Affecting Pulmonary Ventilation

Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...

Pathophysiology of Cardiac Performance

Pathophysiology of Cardiac Performance

Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of resistance training with/without Photobiomodulation on muscle and respiratory function in difficult-to-control asthma: a randomized trial.

Lasers in medical science·2026

Same author

Total adenosine deaminase cases as an inflammatory biomarker of pleural effusion syndrome.

World journal of clinical cases·2025

Same author

Periostin as an important biomarker of inflammatory phenotype T2 in Brazilian asthma patients.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia·2023

Same author

In-hospital severe COVID-19 in a philanthropic tertiary hospital setting: is asthma a concern? A retrospective study.

Sao Paulo medical journal = Revista paulista de medicina·2022

Same author

Shuttle walk test categorization according to the qualifiers of the International Classification of Functioning, Disability, and Health: proposal for use in patients with difficult-to-treat asthma, a cross-sectional study.

Physiotherapy theory and practice·2022

Same author

Diagnostic Accuracy with Total Adenosine Deaminase as a Biomarker for Discriminating Pleural Transudates and Exudates in a Population-Based Cohort Study.

Disease markers·2021

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

Off-pump versus on-pump coronary artery revascularization: effects on pulmonary function.

Ana M R P e Silva¹, Roberto Saad, Roberto Stirbulov

¹Department of Surgery, Santa Casa de São Paulo, Faculty of Medical Sciences, São Paulo, Brazil. ana.mrp@uol.com.br

Interactive Cardiovascular and Thoracic Surgery

|April 21, 2010

Summary

Off-pump coronary artery surgery patients experienced significantly better lung function recovery compared to on-pump surgery patients. This suggests cardiopulmonary bypass impacts pulmonary function differently during cardiac procedures.

More Related Videos

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

Related Experiment Videos

Last Updated: Jun 13, 2026

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Effects of Surgical Masks on Cardiopulmonary Function in Healthy Subjects

Published on: February 12, 2021

Area of Science:

Cardiology
Thoracic Surgery
Pulmonary Medicine

Background:

Coronary artery bypass grafting (CABG) surgery often leads to changes in lung function.
The comparative recovery profiles of off-pump versus on-pump CABG regarding pulmonary function remain debated.

Purpose of the Study:

To prospectively compare pulmonary function recovery in patients undergoing off-pump CABG with an intraluminal shunt versus on-pump CABG.
To evaluate the impact of cardiopulmonary bypass on postoperative lung function.

Main Methods:

A prospective study of 42 patients undergoing CABG, divided into off-pump (n=21) and on-pump (n=21) groups, matched for lesion location.
Patients underwent spirometry, blood gas analysis, and alveolo-arterial oxygen gradient (A-aDO(2)) measurements on postoperative days 4 and 10.
Preoperative pulmonary function was assessed to ensure group comparability.

Main Results:

Both groups showed decreased spirometry, reduced PaO(2) and PaCO(2), and increased A-aDO(2) postoperatively.
Off-pump patients demonstrated significantly better spirometric improvement compared to on-pump patients by postoperative day 10.
Pulmonary function changes differed between the two surgical approaches.

Conclusions:

Coronary artery surgery significantly affects lung function postoperatively, regardless of the technique.
Off-pump CABG with an intraluminal shunt is associated with superior pulmonary function recovery compared to on-pump CABG.
The use of cardiopulmonary bypass appears to have a more pronounced negative impact on lung function recovery.