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Updated: Jun 13, 2026

Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice
Published on: September 13, 2016
Kinetics of liver volume changes in the first year after portal vein embolization
Danton Corrêa1, Lawrence Schwartz, William R Jarnagin
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Objective:
To determine the time course of liver hypertrophy after portal vein embolization (PVE).
Design:
In a cohort study, computed tomography volumetrics were calculated for livers during a 1-year period after PVE.
Setting:
Tertiary liver cancer treatment center.
Patients:
Ten patients who were subjected to PVE and were found subsequently to not be candidates for liver resection.
Intervention:
Right PVE.
Main Outcome Measures:
Left and right liver volumes.
Results:
The left liver continued growing for the entire first year after PVE, while the right liver continued to atrophy. The total volume remained remarkably constant.
Conclusion:
Early PVE during administration of a course of neoadjuvant therapy would be beneficial for enhanced growth of the liver before liver resection.
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