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Maxillary sinusitis caused by Lasiodiplodia theobromae.
1Department of Microbiology, Sri Ramachandra University, Porur, Chennai - 600 116, India.
Indian Journal of Medical Microbiology
|April 21, 2010
Summary
This study reports the first case of fungal sinusitis caused by Lasiodiplodia theobromae, a fungus typically found in tropical regions. The successful treatment involved endoscopic surgery and antifungal therapy.
Area of Science:
- Mycology
- Clinical Medicine
- Infectious Diseases
Background:
- Lasiodiplodia is a genus of fungi, primarily known as plant pathogens in tropical and subtropical zones.
- While associated with human infections like onychomycosis and corneal ulcers, its role in sinusitis is undocumented.
- This highlights a knowledge gap in the clinical spectrum of Lasiodiplodia infections.
Observation:
- A 30-year-old woman presented with a one-week history of intermittent left-sided epistaxis and nasal discharge.
- She also reported two months of intermittent left-sided headache and facial heaviness.
- These symptoms suggested a sino-nasal pathology requiring investigation.
Findings:
- Radiological and mycological evidence confirmed fungal sinusitis.
- Lasiodiplodia theobromae was identified as the causative agent.
- This marks the first reported instance of this fungus causing sinusitis.
Implications:
- This case expands the known clinical manifestations of Lasiodiplodia theobromae infections.
- It underscores the importance of considering fungal pathogens in sino-nasal diseases, even rare ones.
- Early diagnosis and appropriate antifungal treatment are crucial for managing fungal sinusitis.
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