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Updated: Jun 13, 2026

Multiplex Immunohistochemistry Staining for Paraffin-embedded Lung Cancer Tissue
Published on: November 21, 2023
Large cell lung carcinoma with unusual imaging feature, immunophenotype and genetic finding
Jelena Stojsic1, Ruza Stevic, Milica Kontic
1Institute for Lung Diseases and Tuberculosis, Clinical Centre of Serbia, Belgrade, Serbia. dr.jelenastoj@sezampro.rs
Abstract:
We present a case of large cell lung carcinoma in sixty-one year old male with typical lung cancer symptoms but unusual radiological presentation and immunophenotype. Tumor morphological finding related to its radiological finding was suggestive for large cell lymphoma or carcinoma, but its immunophenotype made confusion for pathological diagnosis. No p53 mutations were detected in genetic investigation. Multidisciplinary diagnostic approach to some tumors is useful for their final diagnosis.
