Phenylcarbamoylated beta-CD: pi-acidic and pi-basic chiral selectors for HPLC

Chun Lin1, Wenjun Luo, Sheng Zhang

  • 1Institute of Special Material, South China Normal University, Guangzhou, P. R. China.

Summary

Two novel chiral stationary phases for high-performance liquid chromatography (HPLC) were developed using pi-acidic or pi-basic cyclodextrins. These phases effectively separate enantiomers through hydrogen bonding, steric effects, and pi-acidic-pi-basic interactions.

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