Related Experiment Video
Updated: Jun 13, 2026

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
Published on: February 20, 2017
Performance comparison of 4 portable oxygen concentrators.
Robert L Chatburn1, Thomas J Williams
1Respiratory Institute, M-56, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. chatbur@ccf.org
Portable oxygen concentrators (POCs) vary significantly in performance. Selecting the correct POC setting is crucial for meeting individual patient needs during rest and activity.
Area of Science:
- Biomedical Engineering
- Respiratory Care
Background:
- Portable oxygen concentrators (POCs) are increasingly available in the US.
- Design trade-offs in POCs lead to performance variations.
Purpose of the Study:
- To evaluate and compare the performance of four leading POC models.
- To assess oxygen delivery across different respiratory rates.
Main Methods:
- Tested four POC models (Invacare XPO(2), Respironics EverGo, AirSep FreeStyle, Inogen One).
- Measured oxygen volume per pulse, pulse duration, trigger sensitivity, oxygen concentration, and relative fraction of inspired oxygen (relative F(IO(2))).
- Evaluated performance at respiratory rates of 15, 20, 25, 30, and 35 breaths/min with a tidal volume of 500 mL.
Main Results:
- Significant differences observed in pulse flow, pulse volume, and pulse delivery time among POC models.
- Oxygen purity ranged from 91.9-94.4%.
- Relative F(IO(2)) decreased as respiratory rate increased for all tested POCs.
Conclusions:
- The four evaluated POC models exhibit distinct performance characteristics.
- Clinicians must tailor POC settings to individual patient requirements for both rest and activity.
More Related Videos
Related Concept Videos
Oxygen Delivering System I: Nasal Cannula and Face Mask
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
Respiratory Capacities
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Pulse Oximetry
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...

