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Constructing and Visualizing Models using Mime-based Machine-learning Framework
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The need for precompetitive integrative bionetwork disease model building
1Sage Bionetworks, Seattle, Washington, USA. friend@sagebase.org
Clinical Pharmacology and Therapeutics
|April 22, 2010
Abstract:
If you doubt that there are enormous gaps in the current drug discovery process, you should probably skip to the next article. Yet even while critiques rightly highlight inefficiencies or operational issues, they often miss a fundamental reality: until we better understand diseases as altered bionetworks and view diseases at an individual patient level, efforts to develop effective biomarkers and therapies will be inefficient at best.
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