Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Scattering And Absorption of Light in Planetary Regoliths

Scattering And Absorption of Light in Planetary Regoliths

Published on: July 1, 2019

Comparing membrane simulations to scattering experiments: introducing the SIMtoEXP software.

Norbert Kucerka¹, John Katsaras, John F Nagle

¹Canadian Neutron Beam Centre, National Research Council, Chalk River, ON, K0J 1J0, Canada.

The Journal of Membrane Biology

|April 22, 2010

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lipid-Protein Membrane Structure-Function Characterization using Droplet Interface Bilayers.

Journal of visualized experiments : JoVE·2026

Same author

Review of lipid bilayer structure.

Chemistry and physics of lipids·2026

Same author

Melatonin-Induced Modulation of Cholesterol-Enriched Model Neuronal Membranes.

ACS chemical neuroscience·2026

Same author

Ion transport through reconfigurable nanoparticle-surfactant stabilized droplet interface bilayers.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Bending moduli of mixtures: Diffusional softening and interactions.

Biophysical journal·2026

Same author

Electromechanically induced membrane restructuring enables learning and memory.

Proceedings of the National Academy of Sciences of the United States of America·2025

Same journal

In vitro Reconstitution of Syncytin-2 and MFSD2A Reveals their Functional Tethering in Membrane Fusion Initiation.

The Journal of membrane biology·2026

Same journal

Structural Basis of SERCA Inhibition by Derivatives of di-tert-butylhydroquinone Revealed by X-ray Crystallography.

The Journal of membrane biology·2026

Same journal

Fungal Extracellular Vesicles are Recoverable Across Variable Ultracentrifugation Speeds but Display Species-specific Profiles of Sedimentation.

The Journal of membrane biology·2026

Same journal

Polyproline Modulates Membrane Translocation of Arginine-Rich Cell-Penetrating Peptides: Insights from Molecular Dynamics Simulations.

The Journal of membrane biology·2026

Same journal

Peculiarities of Phosphatidylserine Externalization by Nano- and Microsecond Electric Pulses.

The Journal of membrane biology·2026

Same journal

Protonation of Key Acidic Residues Reveals Binding Features of PCABs to Gastric H, K-ATPase.

The Journal of membrane biology·2026

See all related articles

SIMtoEXP software compares biomembrane simulations with X-ray and neutron scattering data. It calculates and visualizes electron and neutron scattering length density profiles, aiding experimental validation.

Area of Science:

Biophysics
Computational Biology
Materials Science

Background:

Biomembrane structure is crucial for cellular function.
Experimental scattering techniques provide insights into membrane structure.
Comparing simulations with experimental data is essential for validating models.

Purpose of the Study:

To introduce SIMtoEXP, a software package for comparing biomembrane simulations with experimental scattering data.
To enable quantitative analysis of biomembrane structure through simulation-experimental data integration.

Main Methods:

Accepts simulation-derived number density profiles.
Calculates electron density (epsilon(z)) and neutron scattering length density (nu(z)) profiles and their Fourier transforms.
Integrates user-defined component group analysis for volume and density contributions.

More Related Videos

Simulation, Fabrication and Characterization of THz Metamaterial Absorbers

Simulation, Fabrication and Characterization of THz Metamaterial Absorbers

Published on: December 27, 2012

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Published on: October 21, 2018

Related Experiment Videos

Last Updated: Jun 13, 2026

Scattering And Absorption of Light in Planetary Regoliths

Scattering And Absorption of Light in Planetary Regoliths

Published on: July 1, 2019

Simulation, Fabrication and Characterization of THz Metamaterial Absorbers

Simulation, Fabrication and Characterization of THz Metamaterial Absorbers

Published on: December 27, 2012

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Published on: October 21, 2018

Main Results:

Generates graphical representations of simulated density profiles and scattering functions.
Facilitates direct comparison with experimental X-ray and neutron scattering data.
Provides detailed insights into the contribution of individual molecular components to overall membrane properties.

Conclusions:

SIMtoEXP offers a robust platform for validating biomembrane simulations against experimental scattering data.
The software enhances the interpretation of complex biomembrane structures.
It aids in refining simulation models for increased accuracy and predictive power.