Related Experiment Video
Updated: Jun 13, 2026
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Functional reorganization induced by endovascular embolization of a cerebral AVM
R S Marshall1, L Hacein-Bey, W L Young
1Department of Neurology, Neurological Institute, Columbia-Presbyterian Medical Center, New York, New York 10032, USA.
Abstract:
We mapped motor function in a patient with a cerebral arteriovenous malformation (AVM) before and after treatment with endovascular embolization. Functional activation using technetium-99m-hexamethylpropyleneamine single photon emission tomography (99mTc-HMPAO-SPECT) demonstrated a redistribution of regional cerebral blood flow (rCBF) that correlated with clinical improvement. Intravascular feeding artery pressure measurements, serial angiography, and challenge with a pharmacological vasodilator enabled us to explore possible mechanisms of functional reorganization.
