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Streptococcus dysgalactiae subsp. equisimilis Bacteremia, Finland, 1995-2004
Sari Rantala1, Susanna Vahakuopus, Jaana Vuopio-Varkila
1Department of Internal Medicine, Tampere University Hospital, Tampere, Finland. sari.rantala@uta.fi
Emerging Infectious Diseases
|April 23, 2010
Summary
Rare Streptococcus dysgalactiae subsp. equisimilis emm types were linked to severe disease and higher mortality. Common emm types were more frequently associated with skin and soft tissue infections in bacteremia cases.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Background:
- Streptococcus dysgalactiae subsp. equisimilis is a significant cause of bacteremia.
- emm typing is crucial for understanding Streptococcus strains and their virulence.
- Previous research on emm type distribution and clinical outcomes in bacteremia is limited.
Purpose of the Study:
- To investigate the association between emm types of Streptococcus dysgalactiae subsp. equisimilis and clinical outcomes in bacteremia.
- To determine if specific emm types correlate with disease severity and mortality.
- To analyze the clinical manifestations associated with different emm types.
Main Methods:
- Retrospective population-based study design.
- Analysis of 140 episodes of Streptococcus dysgalactiae subsp. equisimilis bacteremia in Finland (1995-2004).
- emm typing of bacterial isolates.
Main Results:
- Rare emm types were significantly associated with more severe disease presentations.
- Increased mortality rates were observed in patients infected with rare emm types.
- Skin and soft tissue infections were more common in cases attributed to common emm types.
Conclusions:
- emm type is a critical factor influencing the clinical course and outcomes of Streptococcus dysgalactiae subsp. equisimilis bacteremia.
- Distinguishing between common and rare emm types can aid in predicting disease severity and patient prognosis.
- Further research into the specific virulence factors of different emm types is warranted.
