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Related Concept Videos

Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences01:17

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
Nuclear Magnetic Resonance (NMR): Overview01:07

Nuclear Magnetic Resonance (NMR): Overview

Nuclear magnetic resonance (NMR) is a phenomenon exhibited by certain nuclei that can absorb characteristic radio frequency radiation under certain conditions. NMR has been extensively applied in molecular spectroscopy and medical diagnostic imaging. In both these applications, the molecule or subject under study is placed in a magnetic field and irradiated with radio frequency energy.
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
¹H NMR: Interpreting Distorted and Overlapping Signals01:02

¹H NMR: Interpreting Distorted and Overlapping Signals

Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...

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Updated: Jun 13, 2026

MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T
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MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T

Published on: January 16, 2021

NMR at very low fields.

Lutz Trahms1, Martin Burghoff

  • 1Physikalisch-Technische Bundesanstalt, Berlin, Germany. lutz.trahms@ptb.de

Magnetic Resonance Imaging
|April 23, 2010
PubMed
Summary
This summary is machine-generated.

Low-field nuclear magnetic resonance (NMR) is experiencing a revival, offering new insights into molecular structure and dynamics. This technique explores unique physical and technical features, including micro-Tesla magnetic resonance imaging.

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Last Updated: Jun 13, 2026

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High-Sensitivity Nuclear Magnetic Resonance at Giga-Pascal Pressures: A New Tool for Probing Electronic and Chemical Properties of Condensed Matter under Extreme Conditions

Published on: October 10, 2014

Area of Science:

  • Physics
  • Chemistry
  • Biophysics

Background:

  • Nuclear Magnetic Resonance (NMR) has a long history, with low-field NMR techniques existing since its inception.
  • Recent years show a resurgence in low-field NMR, diverging from the trend towards high-field instrumentation.
  • This revival is driven by the potential of low-field NMR to reveal novel aspects of molecular structure and dynamics.

Purpose of the Study:

  • To provide a comprehensive overview of low-field NMR.
  • To discuss the unique technical and physical characteristics of low-field NMR.
  • To explore the application of magnetic resonance imaging in ultra-low magnetic fields.

Main Methods:

  • Review of existing literature and technical advancements in low-field NMR.
  • Analysis of physical principles governing NMR in low magnetic fields (micro-Tesla range).
  • Discussion of instrumentation and experimental setups for low-field NMR.

Main Results:

  • Low-field NMR presents distinct signal characteristics and relaxation behaviors compared to high-field NMR.
  • Specific technical adaptations are required for effective low-field NMR experiments.
  • Magnetic Resonance Imaging (MRI) is feasible and offers unique advantages in micro-Tesla fields.

Conclusions:

  • Low-field NMR offers a complementary approach to high-field NMR for studying molecular systems.
  • The revival of low-field NMR is expected to expand the scope of molecular structure and dynamics research.
  • Ultra-low field MRI demonstrates potential for specialized imaging applications.