Related Experiment Video
Updated: Jun 13, 2026
07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
[Serious pulmonary embolism and thromboaspiration]
1Réanimation médicochirurgicale, hôpital St-Roch, CHU de Nice, université Nice Sophia-Antipolis, 4, rue Pierre-Dévoluy, 06006 Nice, France.
Annales Francaises D'Anesthesie Et De Reanimation
|April 23, 2010
Summary
Pulmonary embolism (PE) is a serious condition. Radiological endovascular thrombectomy offers a safe and effective treatment alternative for high-risk patients when conventional methods are contraindicated.
Area of Science:
- Cardiology
- Vascular Medicine
- Interventional Radiology
Background:
- Pulmonary embolism (PE) is a frequent cause of mortality, affecting approximately 3% of patients.
- Polytraumatized and peripartum patients face elevated risks of thromboembolism due to immobility and inflammatory responses.
- Prompt diagnosis and intervention are critical for improving survival rates in PE cases.
Observation:
- Conventional treatment with systemic intravascular thrombolysis carries a high risk of hemorrhage, contraindicating its use in intensive care patients.
- Two intensive care patients with contraindications for thrombolysis were successfully treated for pulmonary embolism.
- The treatment utilized was radiological endovascular thrombectomy.
Findings:
- Radiological endovascular thrombectomy demonstrated successful clot removal in both reported cases.
- This minimally invasive technique circumvented the hemorrhagic risks associated with systemic thrombolysis.
- The procedure was well-tolerated, leading to positive patient outcomes.
Implications:
- Endovascular thrombectomy presents a viable and safer alternative for managing pulmonary embolism in critically ill patients.
- This approach expands treatment options for patients where traditional thrombolysis is not feasible.
- Further research into endovascular thrombectomy for PE could refine protocols and improve patient management strategies.
Related Concept Videos
01:29Pulmonary Embolism I: Introduction
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
01:19Pulmonary Embolism I: Introduction
A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
01:27Pulmonary Embolism III: Nursing Management
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
01:26Pneumothorax-I
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
01:30Venous Thrombosis I: Introduction
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...