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Published on: September 26, 2018
High-risk patients with hypertension: Are we doing enough?
Evelyn Chiao1, John Sobolski, Russ Krienke
1Xcenda, Palm Harbor, Florida, USA.
Insights
Blood pressure control is suboptimal in high-risk patients, with only 46% achieving goals. Diabetics showed particularly low control rates (28%), highlighting a need for more aggressive hypertension management.
Area of Science:
- Cardiology
- Hypertension Management
- Public Health
Background:
- Cardiovascular disease risk is rising, particularly in patients with multiple risk factors.
- Blood pressure (BP) control remains a significant challenge, even with available treatments.
Purpose of the Study:
- To evaluate real-world blood pressure goal attainment in high-risk hypertensive patients.
- To analyze prescribing patterns of antihypertensive medications in these patient groups.
Main Methods:
- Retrospective chart review of 1,917 hypertensive patients from primary care practices (2003-2006).
- Analysis of BP control rates and medication classes based on risk factors: African-American ethnicity, diabetes, advanced age, and BMI ≥25 kg/m².
Main Results:
- Overall BP control rate was 46%, significantly lower (28%) in diabetic patients.
- Elevated systolic BP (>20 mm Hg above recommendation) occurred in 13-20% of patients.
- While 62% received ≥2 antihypertensives, high-risk groups often received ≥3 classes (26-36%).
Conclusions:
- Suboptimal BP control persists in high-risk hypertensive patients despite multiple antihypertensive options.
- Increased awareness and more aggressive treatment strategies are crucial for this population to mitigate poor outcomes.
Abstract:
Despite the increasing risk of cardiovascular disease, especially in patients with multiple risk factors, blood pressure (BP) control remains suboptimal. This study investigated real-world BP goal attainment and prescribing patterns for high-risk patients. A retrospective chart review study was conducted in patients treated by eight large primary care physician group practices between December 2003 and May 2006. A total of 1,917 hypertensive patients were identified with >/=1 risk factors: African-American ethnicity (634); diabetes (851); advanced age (1,123); body mass index (BMI) 25 kg/m(2) (1,614). BP control rate was 46% overall, and similar in the advanced age and overweight/obese subpopulations, but substantially lower (28%) in the diabetic subpopulation. Systolic blood pressure >/=20 mm Hg above the Joint National Committee on Prevention, Detection, Evaluation, and Treatment Report recommendation was found in 13% of the overall, advanced age and overweight/obese subpopulations, and in 20% of diabetics and 18% of African-Americans. Overall, 62% of patients received >/=2 antihypertensive while 36% of diabetics, 31% of African-Americans, 28% of advanced age, and 26% of overweight/obese patients received >/=3 antihypertensive classes. Despite availability of multiple antihypertensive classes, BP control rates were still suboptimal in this study's high-risk patients. There is a need for awareness and more aggressive treatment in high-risk patients given their increased risk of poor outcomes.
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