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Costs associated with cardiovascular events in patients with hypertension in US managed care settings
Mei Sheng Duh1, Nicole M Fulcher, Leigh Ann White
1Analysis Group, Inc., Boston, Massachusetts, USA.
Insights
Cardiovascular events significantly increase healthcare costs for hypertensive patients, especially those with high-risk conditions. Acute myocardial infarction and heart failure incur the highest incremental costs, primarily driven by inpatient services.
Area of Science:
- Health Economics
- Cardiovascular Medicine
- Hypertension Management
Background:
- Hypertension (HTN) is a prevalent condition often coexisting with high-risk factors.
- Cardiovascular (CV) events represent significant complications of uncontrolled hypertension.
- Understanding the economic burden of CV events in specific patient subgroups is crucial for resource allocation.
Purpose of the Study:
- To quantify the incremental healthcare costs associated with cardiovascular events in high-risk and compelling indication subgroups of hypertensive patients.
- To compare costs between hypertensive patients with and without CV events, and before and after CV events.
Main Methods:
- Retrospective analysis of claims data from privately insured individuals diagnosed with hypertension between 2004 and 2006.
- Regression-adjusted per-member-per-month healthcare costs were estimated post-cardiovascular event (CVE).
- Costs were analyzed across inpatient, outpatient, and prescription drug components for various CV events.
Main Results:
- Healthcare costs were significantly higher across all components for hypertensive patients experiencing CV events compared to controls.
- Acute myocardial infarction (MI) and congestive heart failure (CHF) demonstrated the largest incremental total healthcare costs.
- Inpatient costs constituted the primary driver of healthcare expenditures in the first quarter following a CV event.
Conclusions:
- Cardiovascular events are expensive complications of hypertension, particularly in high-risk populations.
- The findings highlight the substantial economic impact of managing CV events in patients with conditions like diabetes, chronic kidney disease, and prior stroke.
- Effective hypertension management and prevention of CV events are essential to mitigate significant healthcare expenditures.
Abstract:
Study quantified incremental cost of cardiovascular (CV) events in 6 high-risk and compelling indication subgroups: post-myocardial infarction (MI), diabetes, diabetic nephropathy, elderly, chronic kidney disease, and prior stroke. Based on claims data from privately insured individuals with 2+ hypertension (HTN) diagnoses in 2004-2006, we estimated regression-adjusted per-member-per-month healthcare costs after CVE. Costs were compared between patients with and without a CV events, and before and after CV events in each subgroup. The following CVevents were studied: acute MI, acute coronary syndrome, angina, ventricular arrhythmia, atrial arrhythmia, heart failure, coronary artery disease, left ventricular hypertrophy, stroke, and sinus tachycardia. Of 1,598,890 HTN patients, 510,118 had >/=1 CV event. Compared with controls, healthcare costs among patients with events were significantly greater across all cost components (inpatient, outpatient, and prescription drug). Acute MI and congestive heart failure generally had the largest incremental total healthcare costs. First-quarter post-event costs were attributable to inpatient costs. CV events are costly sequelae of hypertension in high-risk and CI subgroups.
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