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Updated: Jun 13, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary artery anomalies: detection on coronary artery calcium scoring scan
Hye-Jeong Lee1, Young Jin Kim, Jin Hur
1Department of Diagnostic Radiology, Severance Hospital, Yonsei University College of Medicine, Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea.
Insights
Coronary artery calcium scans accurately identify coronary anomalies and high-risk interarterial courses. This non-invasive imaging technique shows high sensitivity and specificity, aiding in diagnosis.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Coronary anomalies can increase the risk of adverse cardiovascular events.
- Accurate identification of coronary anomalies and their courses is crucial for risk stratification and management.
- CT coronary angiography is the gold standard but involves radiation and contrast agents.
Purpose of the Study:
- To assess the diagnostic accuracy of coronary artery calcium (CAC) scanning in detecting coronary anomalies.
- To evaluate the ability of CAC scanning to identify potentially high-risk interarterial courses of coronary arteries.
- To compare the performance of CAC scanning against CT coronary angiography as the reference standard.
Main Methods:
- Retrospective analysis of CAC scans from 190 patients (95 with coronary anomalies, 95 controls).
- Evaluation by three radiologists for presence of coronary anomalies and interarterial courses.
- Calculation of sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).
Main Results:
- High interobserver agreement for evaluating coronary anomalies (kappa=0.81) and interarterial courses (kappa=0.92).
- CAC scanning demonstrated high diagnostic performance for coronary anomalies (sensitivity 79-80%, specificity 95-98%).
- CAC scanning showed excellent accuracy for interarterial courses (sensitivity 88-91%, specificity 95-97%).
Conclusions:
- Coronary artery calcium scanning is a highly accurate tool for detecting coronary anomalies.
- CAC scanning effectively identifies potentially high-risk interarterial courses.
- This non-invasive method offers a valuable alternative or adjunct for evaluating coronary artery anatomy.
Objective:
The objective of this study was to evaluate the accuracy of coronary artery calcium scanning in identifying coronary anomalies and potentially high-risk interarterial courses.
Materials And Methods:
Ninety-five consecutive patients who were diagnosed with a coronary anomaly on CT coronary angiography were enrolled, and 95 age- and sex-matched individuals in whom any coronary anomalies were excluded on CT coronary angiography were used as control subjects (total, 190 patients; 106 men and 84 women; mean age, 58 +/- 12 years). The coronary artery calcium scan for each patient was retrospectively evaluated by three radiologists for the presence of coronary anomalies and the presence of an interarterial course in cases of suspected anomaly. Interobserver agreement was assessed. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a coronary artery calcium scan for coronary anomalies and their interarterial courses were calculated, with CT coronary angiography as the reference standard.
Results:
Almost perfect interobserver agreement was achieved in evaluating coronary anomalies and interarterial courses (kappa = 0.81 and 0.92, respectively). We achieved a high grade of diagnostic performance of coronary artery calcium scanning in detecting coronary anomalies (sensitivity, 79-80%; specificity, 95-98%; PPV, 94-97%; and NPV, 82-83%) and interarterial courses (sensitivity, 88-91%; specificity, 95-97%; PPV, 84-91%; and NPV, 97%).
Conclusion:
Coronary anomalies and interarterial courses were detected with great accuracy on coronary artery calcium scans.
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