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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Prevalence, pathogenesis, and impact of atrial fibrillation

Cynthia A Sanoski1

  • 1Department of Pharmacy Practice, Jefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107-5233, USA. cynthia.sanoski@jefferson.edu

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|April 23, 2010
PubMed

Insights

Atrial fibrillation (AF), an age-related heart rhythm disorder, is increasing in prevalence and causing significant health issues. Understanding its causes and risks helps in managing AF and preventing complications like stroke.

Area of Science:

  • Cardiology
  • Gerontology
  • Public Health

Background:

  • Atrial fibrillation (AF) is a prevalent cardiac arrhythmia, particularly in aging populations.
  • AF contributes significantly to morbidity and mortality, with increasing rates of hospitalization and treatment costs.
  • Structural heart disease, including coronary heart disease, hypertension, heart failure, and valvular heart disease, is closely linked to AF development.

Observation:

  • The prevalence of AF is rising, presenting a growing public health challenge.
  • AF is associated with substantial morbidity and mortality, impacting patient outcomes.
  • Risk factors for AF are diverse, involving structural heart disease and other contributing elements.

Findings:

  • The incidence of atrial fibrillation (AF) is increasing, especially in older adults.
  • Structural heart conditions are primary risk factors and comorbidities for AF.
  • Risk stratification tools can estimate the likelihood of AF and associated ischemic stroke.

Implications:

  • Effective management of AF requires a thorough understanding of its pathogenesis and risk factors.
  • Utilizing risk-scoring systems can aid in personalized treatment strategies for AF.
  • Minimizing the morbidity, mortality, and economic burden of AF is achievable through informed clinical practice.
Abstract

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