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Equine H7N7 influenza A viruses are highly pathogenic in mice without adaptation: potential use as an animal model

Y Kawaoka1

  • 1Department of Virology and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38101.

Journal of Virology
|July 1, 1991
PubMed

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Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...