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Related Concept Videos

Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer Disease ll: Pathophysiology01:23

Alzheimer Disease ll: Pathophysiology

Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.

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Related Experiment Video

Updated: Jun 13, 2026

Operation Procedure and Precautions of Thread-Embedding Acupuncture Therapy in Alzheimer
05:54

Operation Procedure and Precautions of Thread-Embedding Acupuncture Therapy in Alzheimer

Published on: May 10, 2024

[Alzheimer's disease].

H Jedidi1, Z Jedidi, E Salmon

  • 1Service de Neurologie, CHU de Liège, Centre de la mémoire, Aspirant FNRS.

Revue Medicale De Liege
|April 24, 2010
PubMed
Summary
This summary is machine-generated.

Alzheimer's disease, a common neurodegenerative condition in older adults, presents a significant public health challenge. Personalized treatment plans, including non-pharmacological strategies, are crucial for managing this condition.

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Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
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Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke

Published on: March 22, 2016

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Last Updated: Jun 13, 2026

Operation Procedure and Precautions of Thread-Embedding Acupuncture Therapy in Alzheimer
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Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
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Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke

Published on: March 22, 2016

Area of Science:

  • Neurology
  • Geriatrics
  • Public Health

Background:

  • Alzheimer's disease is the most prevalent neurodegenerative disorder affecting individuals over 60.
  • Its high prevalence makes it a critical public health issue due to significant functional decline.
  • This discussion centers on a clinical case to explore diagnostic and therapeutic strategies.

Observation:

  • The abstract presents a clinical case of Alzheimer's disease in an elderly patient.
  • It highlights the need for a detailed diagnostic and therapeutic discussion.
  • The case serves as a platform to address the complexities of managing Alzheimer's disease.

Findings:

  • Effective management requires individualized treatment adjustments for each patient.
  • Non-pharmacological therapeutic approaches are essential and should not be overlooked.
  • A comprehensive approach integrating various strategies is key to patient care.

Implications:

  • Tailored treatment plans can improve patient outcomes and quality of life.
  • Integrating non-pharmacological interventions may mitigate disease progression and associated burdens.
  • This approach emphasizes a holistic view of Alzheimer's disease management, addressing both clinical and social aspects.