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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...

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The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
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Structural model for osteoporosis preventing behavior in men.

Margaret O Doheny1, Carol A Sedlak, Rosalie J Hall

  • 1Kent State University, Kent, OH, USA. pdoheny@kent.edu

American Journal of Men'S Health
|April 24, 2010
PubMed
Summary

Bone mineral density screening increased calcium intake in men over 50, particularly after receiving personalized dual-energy X-ray absorptiometry (DXA) results. Health beliefs also influenced initial calcium consumption.

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Area of Science:

  • Gerontology
  • Nutritional Science
  • Radiology

Background:

  • Osteoporosis prevention is crucial for men over 50.
  • Understanding factors influencing calcium intake and exercise is vital for bone health.
  • Personalized health information may impact health behaviors.

Purpose of the Study:

  • To evaluate the impact of bone mineral density screening on calcium intake and exercise in healthy men over 50.
  • To assess the role of dual-energy X-ray absorptiometry (DXA) feedback on health behaviors.
  • To explore the relationship between health beliefs, motivation, and calcium intake.

Main Methods:

  • A 1-year longitudinal randomized clinical trial involving 196 healthy men over 50.
  • Experimental group received personal bone density information via DXA.
  • Data collected via questionnaires at baseline, 6 months, and 12 months; analyzed using structural equation modeling.

Main Results:

  • The experimental group showed significantly higher calcium intake at 6 months post-DXA screening compared to the control group.
  • No significant direct effect on calcium intake was observed at 12 months.
  • Initial calcium intake was predicted by health beliefs and health motivation; personal DXA results significantly correlated with increased calcium intake.

Conclusions:

  • Personalized bone density screening, specifically DXA results, can positively influence calcium intake in older men.
  • Health beliefs and motivation are important predictors of baseline calcium intake.
  • Targeted screening interventions may be effective for promoting bone-healthy behaviors in aging populations.