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Updated: Jun 13, 2026

The Combined Use of Transcranial Direct Current Stimulation and Robotic Therapy for the Upper Limb
Published on: September 23, 2018
Recent advances in combined modality therapy
Michelle L Mierzwa1, Mukesh K Nyati, Meredith A Morgan
1Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA. mierzwa@uc.edu.
Abstract:
Combined modality therapy emerged from preclinical data showing that carefully chosen drugs could enhance the sensitivity of tumor cells to radiation while having nonoverlapping toxicities. Recent advances in molecular biology involving the identification of cellular receptors, enzymes, and pathways involved in tumor growth and immortality have resulted in the development of biologically targeted drugs. This review highlights the recent clinical data in support of newer generation cytotoxic chemotherapies and systemic targeted agents in combination with radiation therapy.
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