[Cornea guttata and Fuchs' endothelial-epithelial dystrophy. Clinico-histologic study of 73 patients]

In a retrospective, clinico-histological study, 84 corneas from 73 patients with diagnosed Fuchs' dystrophy (FD) were examined after penetrating keratoplasty. Seven types of posterior corneal degeneration were found: six with diversely arranged and pronounced guttae and a thickened Descemet's membrane, and a seventh with no guttae in either eye. This last variant appeared histologically in only two patients. Whether it represents a different syndrome can only be speculated. Our study showed, however, that the frequency of cornea guttata (CG) in FD is statistically significant in all the histological variants.