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Updated: Jun 13, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Neurocognitive function and cardiovascular disease.

Shari R Waldstein1, Carrington Rice Wendell

  • 1Department of Psychology, University of Maryland, Baltimore County, Baltimore, MD 21250, USA. waldstei@umbc.edu

Journal of Alzheimer'S Disease : JAD
|April 24, 2010
PubMed
Summary
This summary is machine-generated.

Cardiovascular disease impacts brain function and cognition, potentially predicting cognitive decline. Early intervention for cardiovascular risk factors may prevent cognitive impairment and dementia.

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Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

Area of Science:

  • Neuroscience
  • Cardiology
  • Gerontology

Background:

  • Cardiovascular (CV) diseases and risk factors detrimentally affect brain health and neurocognitive function.
  • Impairments in cognition, including executive functions and memory, are linked to CV risk and disease severity across age groups.
  • The potential for distinct subgroups of cognitive impairment and the predictive role of neurocognitive performance itself remain underexplored.

Purpose of the Study:

  • To explore the relationship between cardiovascular health and neurocognitive function.
  • To investigate whether neurocognitive performance patterns can predict the conversion to mild cognitive impairment (MCI) and dementia.
  • To highlight the need for comprehensive neurocognitive assessments alongside other biomarkers for predictive modeling.

Main Methods:

  • Review of existing literature on cardiovascular disease, risk factors, and their impact on cognitive function.
  • Analysis of studies examining cognitive decrements across various domains (executive functions, attention, memory, etc.).
  • Discussion of future research directions, emphasizing integrated assessment approaches.

Main Results:

  • A broad spectrum of CV risk factors and diseases are associated with cognitive function decrements.
  • Cognitive decline occurs across multiple domains and is linked to increasing CV risk and disease severity.
  • The predictive capacity of neurocognitive performance for MCI and dementia conversion requires further investigation.

Conclusions:

  • Neurocognitive function is significantly impacted by cardiovascular disease and risk factors.
  • Neurocognitive performance patterns, integrated with other data, may predict future cognitive decline, MCI, and dementia.
  • Aggressive prevention and early intervention of CV risk are crucial for mitigating cognitive impairment and dementia.