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Profile of asymmetrical retinopathy of prematurity in twins
Rajvardhan Azad1, Parijat Chandra, Sourabh D Patwardhan
1Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110 029, India.
Background:
In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors.
Objective:
To study the profile of asymmetric ROP in twins
Design:
Retrospective study.
Setting:
Tertiary ROP referral eye hospital.
Materials And Methods:
The profile of 56 pairs of twins with ROP were studied and analyzed for differences in zone or need for treatment, while studying possible causes for the varied outcome.
Results:
In 45 pairs of twins (80%) the disease progressed identically in both eyes, while in 11 pairs (20%) the ROP showed differences in zone or need for treatment. Four of these pairs were discordant. In 3 of these 4 pairs, the heavier birth weight twin had a more severe ROP course.
Conclusions:
Twins can present with asymmetric ROP course, and it is therefore essential to examine both twins as per screening protocols.
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