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Related Concept Videos

What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

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Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration
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[Breast cancer].

Yuki Saito1, Yasuhiro Suzuki, Takuho Okamura

  • 1Department of Breast and Endocrine Surgery, Tokai University School of Medicine, 143 Shimokasuya, Kanagawa, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|April 24, 2010
PubMed
Summary
This summary is machine-generated.

This study compares the Japanese breast cancer clinical practice guideline with international standards. It aims to ensure consistent, high-quality breast cancer treatment globally by evaluating guideline alignment with global research and practices.

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Area of Science:

  • Oncology
  • Clinical Practice Guidelines
  • Evidence-Based Medicine

Context:

  • Breast cancer treatment involves diverse modalities like chemotherapy, hormone therapy, targeted therapy, radiotherapy, and surgery.
  • Clinical practice guidelines are essential for standardizing care and ensuring equitable treatment quality across Japan.
  • International clinical trials necessitate aligning national guidelines with global standards.

Purpose:

  • To compare the Japanese Breast Cancer Society's guideline with prominent international breast cancer guidelines.
  • To identify areas of concordance and divergence between national and global treatment recommendations.
  • To inform potential updates for harmonizing Japanese guidelines with international best practices.

Summary:

  • The Japanese Breast Cancer Society's clinical practice guideline was systematically compared against widely adopted international guidelines.
  • Analysis focused on treatment recommendations for chemotherapy, hormone therapy, molecular targeted therapy, radiotherapy, and surgery.
  • The study evaluates the guideline's alignment with current international research and clinical trial outcomes.

Impact:

  • Facilitates the standardization of breast cancer care on a global scale.
  • Promotes equitable access to high-quality breast cancer treatment for patients worldwide.
  • Provides a foundation for updating the Japanese guideline to reflect international consensus and advancements.