Related Experiment Video
Updated: Jun 13, 2026

06:37
Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
Published on: October 20, 2010
[Brazilian gamma detection device for sentinel lymph node biopsy]
Renato Santos de Oliveira Filho1, Andréia Bufoni Farah, Fábio Eduardo da Costa
1Hospital Israelita Albert Einstein, São Paulo, BR. renato.prevencao@terra.com.br
Revista Do Colegio Brasileiro De Cirurgioes
|April 24, 2010
Summary
A new Brazilian gamma detection device (IPEN) effectively aids in sentinel lymph node biopsy (SLNB) for cancer patients. This intra-operative tool successfully located sentinel nodes, proving comparable to existing technology without compromising patient safety.
Area of Science:
- Oncology
- Surgical Innovation
- Medical Device Technology
Background:
- Sentinel lymph node biopsy (SLNB) is crucial for cancer staging.
- Accurate intra-operative detection of sentinel nodes (SN) improves surgical outcomes.
- Existing gamma detection devices are essential for SLNB procedures.
Purpose of the Study:
- To evaluate the effectiveness of a novel intra-operative gamma detection device developed in Brazil (IPEN).
- To compare the performance of the IPEN device with a standard gamma detection device during SLNB.
- To assess the ease of SN identification and the safety of using the IPEN device.
Main Methods:
- Forty patients with melanoma or breast cancer underwent SLNB.
- Lymphoscintigraphy was performed pre-operatively.
- Both the Neoprobe 1500 and the IPEN device were used for intra-operative gamma detection and SN localization.
Main Results:
- The study included 33 breast cancer and 7 melanoma patients.
- Sentinel nodes were successfully identified in all but one patient.
- No significant statistical difference was found in measurements between the IPEN and Neoprobe devices, with SNs easily located by surgeons.
Conclusions:
- Sentinel lymph node biopsy was successfully performed using both gamma detection devices.
- The Brazilian-developed IPEN device demonstrated comparable effectiveness to existing technology.
- The IPEN device can be utilized for SLNB without adverse effects on patient outcomes.
