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Updated: Jun 13, 2026
08:02
In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
Published on: January 22, 2020
Modulating immune responses and inflammation
Christoph Leder1, Melanie Ziegler, Meinrad Gawaz
1Medizinische Klinik III, Kardiologie und Kreislauferkrankungen, Eberhard Karls-Universität Tübingen, Tübingen, Germany. christoph.leder@med.uni-tuebingen.de
Seminars in Thrombosis and Hemostasis
|April 24, 2010
Summary
New treatments are needed for immune and cardiovascular diseases. This review covers therapeutic targets for immune responses, benefiting autoimmune, inflammatory, and cardiovascular conditions like myocarditis and atherosclerosis.
Area of Science:
- Cardiovascular Immunology
- Immunology
- Pharmacology
Background:
- Urgent need for novel disease-modifying therapies for immune and immune-related cardiovascular diseases.
- Current therapeutic development includes small molecules, natural compounds, and biopharmaceuticals.
- Immune-related cardiovascular diseases include myocarditis and atherosclerosis.
Purpose of the Study:
- To summarize potential intervention points for ongoing immune responses.
- To list examples of therapeutic strategies targeting these immune mechanisms.
- To highlight the potential benefits for cardiovascular immunology research.
Main Methods:
- Literature review of innovative therapies for immune diseases.
- Analysis of therapeutic targets for immune response modulation.
- Compilation of examples of developed therapeutic exploitations.
Main Results:
- Identified key intervention points in immune responses.
- Cataloged diverse therapeutic approaches targeting these points.
- Highlighted the translational potential for cardiovascular immunology.
Conclusions:
- Advances in treating general immune and inflammatory diseases are highly relevant for immune-related cardiovascular diseases.
- Continued research in cardiovascular immunology is crucial.
- Therapeutic strategies targeting immune responses offer promise for conditions like myocarditis and atherosclerosis.
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