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[Semiological profile of gout in patients with AA, AS and AC hemoglobins]
Owonayo Oniankitan1, Eyram Fianyo, Prénam Houzou
1Service de rhumatologie, CHU-Tokoin de Lomé, Togo.
Insights
This study found no significant difference in gout expression or risk factors among patients with AA, AS, or AC hemoglobin. Hemoglobin type does not appear to influence gout diagnosis or etiological investigation.
Area of Science:
- Rheumatology
- Hematology
- Genetics
Context:
- Gout is a common inflammatory arthritis.
- Hemoglobin variants (AS, AC) are prevalent in certain populations.
- Understanding risk factors for gout is crucial for patient management.
Purpose:
- To investigate potential differences in gout presentation and risk factors based on hemoglobin type (AA, AS, AC).
- To analyze data from patients treated at the Lomé Teaching Hospital rheumatology clinic.
Summary:
- A 17-year retrospective study analyzed 214 gout patients (14902 total patients), categorizing them by hemoglobin type: AA (147), AS (41), and AC (26).
- Common risk factors identified included alcoholism, obesity, and hypertension in 97% of patients.
- No statistically significant differences in semiological expression or risk factors were observed between hemoglobin groups.
Impact:
- The findings suggest that AS and AC hemoglobin types do not influence the clinical expression of gout.
- This indicates that hemoglobin electrophoresis results should not alter the diagnostic approach or etiological investigation in gout patients.
- Highlights the importance of established risk factors in gout management irrespective of hemoglobin type.
Aim:
To search a possible difference in gout and in the risk factors for gout expression according to the of hemoglobin in patients seen at the lomé teaching hospital rheumatology clinic (Togo).
Patients And Methods:
Medical records of patients seen during 17 years were studied. The patients affected by the gout and answering New York criteria have been included. All patients object of the comparison, benefitted from a hemoglobin electrophoresis and the search of possible risk factors for gout.
Results:
Among the 14902 patients seen over a 17 year period, 214 had gout (210 males, 4 famales). These 214 patients were carriers of an AA hemoglobin (147 cases), of an AS hemoglobin (41 cases), or of an AC hemoglobin (26 cases). The alcoholism, the obesity, and the arterial hypertension were the main risk factors associated with gout in 207 patients (97%). Semiological and risk factors comparison according to the type of hemoglobin didn't show statistically significant difference.
Conclusion:
it results from this study that the AS hemoglobin and AC hemoglobin don't exercise any influence on the gout semiological expression. Thus, the presence of one of these hemoglobins in gout patient must exercise no influence in the diagnostic gait and in the etiological investigation.
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