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Changes in ocular response analyzer parameters after LASIK.

Shihao Chen1, Ding Chen, Jianhua Wang

  • 1Wenzhou Medical College, Wenzhou, Zhejiang, China.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|April 27, 2010
PubMed
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Myopic LASIK surgery temporarily reduces corneal biomechanical properties, including corneal hysteresis and corneal resistance factor. These changes show minimal recovery by three months and may impact intraocular pressure measurements.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Ocular Biomechanics

Background:

  • Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery for myopia.
  • Understanding the impact of LASIK on corneal biomechanics is crucial for patient safety and accurate intraocular pressure (IOP) assessment.

Purpose of the Study:

  • To investigate the changes in Ocular Response Analyzer parameters following myopic LASIK surgery.
  • To assess the short-term recovery of corneal biomechanical properties after LASIK.

Main Methods:

  • Prospective study of 30 myopic patients (60 eyes) undergoing bilateral LASIK.
  • Ocular Response Analyzer used to measure corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated IOP (IOPg), and corneal-compensated IOP (IOPcc) pre- and post-operatively.

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  • Central corneal thickness (CCT) and flap thickness measured using optical coherence tomography.

    • Main Results:

    • Postoperatively, CH, CRF, IOPg, IOPcc, and CCT significantly decreased (P<.01).
    • A partial recovery of CH, CRF, IOPg, IOPcc, and CCT was observed between 10 days and 3 months (P<.05).
    • Ablation depth correlated more strongly with changes in CRF than CH; CH changes were negatively correlated with flap thickness.

    Conclusions:

    • Corneal biomechanical properties (CH and CRF) are reduced 10 days after myopic LASIK.
    • Minimal recovery (approx. 10%) of these properties occurs by 3 months post-surgery.
    • The alterations in corneal biomechanics following LASIK may influence the accuracy of IOP measurements.