Related Experiment Video
Updated: Jun 13, 2026

Establishing a Porcine Ex Vivo Cornea Model for Studying Drug Treatments against Bacterial Keratitis
Published on: May 12, 2020
Topical piperacillin/tazobactam for recalcitrant pseudomonas aeruginosa keratitis
Fiona L M Chew1, T K Soong, Hoy Choong Shin
1Department of Ophthalmology, Faculty of Medicine, University of Malaya, Jalan Universiti, Kuala Lumpur, Wilayah Persekutuan 50603, Malaysia. sabrefmin@yahoo.co.uk
Purpose:
To report the treatment of therapy-resistant Pseudomonas aeruginosa keratitis with topical piperacillin/tazobactam.
Methods:
Retrospective report of 3 cases.
Results:
Three patients with P. aeruginosa keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of keratitis occurred upon commencement of topical piperacillin/tazobactam.
Conclusion:
Therapy-resistant P. aeruginosa keratitis acquired from the community is becoming an increasing problem. Topical piperacillin/tazobactam is an option for the treatment of therapy-resistant P. aeruginosa keratitis.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Clinical Significance of Antibiotic Resistance