Related Experiment Video
Updated: Jun 13, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Risk factors for suspected developmental delay at age 2 years in a Brazilian birth cohort
Danilo R de Moura1, Jaderson C Costa, Iná S Santos
1Departamento Materno-Infantil, Universidade Federal de Pelotas, Pelotas, RS, Brasil. drolimdemoura@gmail.com
Insights
This study identified key risk factors for suspected developmental delay (SDD) in 2-year-olds. Early screening and interventions targeting factors like maternal education and home environment can improve child development outcomes.
Area of Science:
- Pediatrics
- Developmental Psychology
- Public Health
Background:
- Child development is crucial for lifelong potential.
- Epidemiological studies identify factors influencing development.
- Early identification of developmental delays is essential for timely intervention.
Purpose of the Study:
- To identify risk factors for suspected developmental delay (SDD) at age 2 years.
- To inform public health policies and pediatric interventions for preventing developmental delays.
- To analyze a comprehensive set of maternal, child, and environmental factors associated with SDD.
Main Methods:
- Utilized data from the 2004 Pelotas Birth Cohort in Brazil.
- Administered the Battelle Screening Developmental Inventory (BSDI) at age 2 years.
- Employed multivariable Poisson regression with confounder adjustment to determine risk factors.
Main Results:
- 3.3% of children screened positive for SDD.
- Key risk factors included early screening positive results, low Apgar scores, low maternal education, lower socioeconomic status, gestational diabetes, short birth intervals, lack of story-telling, limited home literature, low birth weight, preterm birth, insufficient antenatal care, prior hospitalization, and male sex.
- Prevalence ratios (PR) and 95% confidence intervals [95% CI] were calculated for each factor.
Conclusions:
- Identified multiple modifiable and non-modifiable risk factors for SDD.
- Findings can guide targeted interventions to support child development.
- Highlights the importance of socioeconomic and environmental factors in early childhood development.
Abstract:
Many children are at risk of not achieving their full potential for development. Epidemiological studies have the advantage of being able to identify a number of associated factors potentially amenable to intervention. Our purpose was to identify risk factors for suspected developmental delay (SDD) at age 2 years among all children born in the city of Pelotas, Brazil, in 2004. This study was part of the 2004 Pelotas Birth Cohort. The Battelle Screening Developmental Inventory (BSDI) was administered to cohort children at age 2 years. A hierarchical model of determination for SDD with confounder adjustment was built including maternal sociodemographic, reproductive and gestational characteristics, as well as child and environmental characteristics. Multivariable analysis was carried out using Poisson regression. Prevalence ratios (PR) and 95% confidence intervals [95% CI] were calculated. In the results, 3.3% of the 3869 children studied screened positive for SDD. After confounder control, children more likely to show SDD were: those with positive BSDI at age 12 months (PR = 5.51 [3.59, 8.47]); with 5-min Apgar <7 (PR = 3.52 [1.70, 7.27]); with mothers who had <4 years of schooling (PR = 3.35 [1.98, 5.66]); from social classes D and E (PR = 3.00 [1.45, 6.19]); with a history of gestational diabetes (PR = 2.77 [1.34, 5.75]); born <24 months after the last sibling (PR = 2.46 [1.42, 4.27]); were not told child stories in the preceding week (PR 2.28 [1.43, 3.63]); did not have children's literature at home (PR = 2.08 [1.27, 3.39]); with low birthweight (PR = 1.75 [1.00, 3.07]); were born preterm (PR = 1.74 [1.07, 2.81]); with <6 antenatal care appointments (PR = 1.70 [1.07, 2.68]); with history of hospitalisation (PR = 1.65 [1.09, 2.50]); and of male sex (PR = 1.43 [1.00, 2.04]). These risk factors may constitute potential targets for intervention by public policies and may provide help to paediatricians in preventing developmental delay.
Related Concept Videos
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Introduction to Developmental Psychology
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Bias in Epidemiological Studies
Conduct Disorder
