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Related Experiment Video

Updated: Jun 13, 2026

Measuring Psoriasis Severity at Home

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Psoriatic arthritis.

Uwe Wollina¹, Leonore Unger, Birgit Heinig

¹Department of Dermatology and Allergology, Hospital Dresden-Friedrichstadt, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany. wollina-uw@khdf.de

Dermatologic Therapy

|April 27, 2010

Summary

Psoriatic arthritis (PSA) is an inflammatory joint disease linked to psoriasis, affecting joints and causing symptoms like enthesitis. Established treatments include DMARDs and TNF-alpha inhibitors, with new drugs in trials.

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Last Updated: Jun 13, 2026

Measuring Psoriasis Severity at Home

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

Rheumatology
Dermatology
Immunology

Background:

Psoriatic arthritis (PSA) is an inflammatory joint disease associated with psoriasis.
It is part of the seronegative spondylarthropathies group.
PSA characteristically affects peripheral joints and the axial skeleton, with enthesitis and dactylitis as key extracutaneous manifestations.

Purpose of the Study:

To review current drug and physical treatment options for psoriatic arthritis.
To highlight established therapies and emerging treatments.
To discuss the impact of treatments on quality of life and long-term outcomes.

Main Methods:

Literature review of existing data on psoriatic arthritis treatments.
Analysis of established therapies, including disease-modifying antirheumatic drugs (DMARDs) and tumor necrosis factor alpha (TNF-alpha) inhibitors.
Examination of ongoing clinical trials for new therapeutic agents.

Main Results:

Disease-modifying antirheumatic drugs (DMARDs) and tumor necrosis factor alpha (TNF-alpha) inhibitors are established therapies for PSA.
These treatments significantly improve quality of life and long-term outcomes for patients.
Anterior uveitis affects approximately 25% of PSA patients.
Nail disease shows a strong correlation with joint disease severity.

Conclusions:

Established therapies like DMARDs and TNF-alpha inhibitors are crucial for managing psoriatic arthritis.
Ongoing research and clinical trials are exploring new drug options to further improve patient outcomes.
Comprehensive management addressing both joint and extracutaneous manifestations is essential for psoriatic arthritis patients.