Related Experiment Video
Updated: Jun 13, 2026

Exploring the Longissimus Muscle: Unraveling its Correlation with Meat Quality in Bos indicus and Crossbred Bulls
Published on: July 12, 2024
Changes in muscle gene expression related to metabolism according to growth potential in young bulls
Carine Bernard1, Isabelle Cassar-Malek, Gilles Renand
1Institut de l'Elevage, Département Génétique, Service Aptitude et Sélection des Races Allaitantes, 149 rue de Bercy, 75595 Paris cedex 12, France.
Abstract:
To analyse the effects of genetic selection in favour of high muscle development on muscle gene expression, oligonucleotide microarrays were used to compare the transcriptome of Longissimusthoracis muscle from 15- and 19-month-old Charolais bull calves divergently selected for high (H) or low (L) muscle growth. Transcriptome data revealed that about two thirds of the genes involved in glycolysis were up-regulated at 15 and at 19months of age in H animals. Lastly, some differentially expressed genes were associated with muscle mass in the carcass (FGF6, PLD2) independently of fat deposition and meat quality. Selection for muscle growth potential is associated with modified expression of some genes involved in growth, and also with increased expression of genes involved in glycolysis. Furthermore, this change in muscle metabolism is likely to be dissociated from fat deposition and beef quality, providing new criteria for genetic selection in favour of muscle growth.
Related Concept Videos
Cell Specific Gene Expression
Formation of Muscle Fibers from Myoblasts
Muscle progenitor cells (MPCs) are formed from the myotomes. MPCs express genes that encode the transcription factors Pax3 and Pax7. Along with Pax 3/7, other transcription factors...
Stringent Response in E. coli
Regulation of Metabolism
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Master Transcription Regulators

