Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Root Mean Square00:57

Root Mean Square

If in an experiment, data values have a probability of being both positive and negative, neither the arithmetic mean, the geometric mean, nor the harmonic mean can be used to calculate the central tendency of the data set. In particular, if the positive and negative values are equally likely, the arithmetic mean is close to zero.
For example, consider the velocity of gas molecules in a container. The gas molecules are moving in different directions, which might impart positive and negative...
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...
Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiovascular risk and hippocampal-cognitive coupling in Alzheimer's disease.

medRxiv : the preprint server for health sciences·2026
Same author

Ventricular enlargement is associated with early Alzheimer's disease pathophysiology.

Brain communications·2026
Same author

Choroidal-ventricular system abnormalities are linked to amyloid-β aggregation in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Quantitative susceptibility mapping of the brain is associated with inflammatory changes in Alzheimer's disease related areas.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2026
Same author

Alzheimer's Imaging Consortium.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Alzheimer's Imaging Consortium.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Related Experiment Video

Updated: Jun 13, 2026

Troubleshooting and Quality Assurance in Hyperpolarized Xenon Magnetic Resonance Imaging: Tools for High-Quality Image Acquisition
09:55

Troubleshooting and Quality Assurance in Hyperpolarized Xenon Magnetic Resonance Imaging: Tools for High-Quality Image Acquisition

Published on: January 5, 2024

Robust Rician noise estimation for MR images.

Pierrick Coupé1, José V Manjón, Elias Gedamu

  • 1McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University 3801, University Street, Montreal, Canada H3A 2B4. pierrick.coupe@gmail.com

Medical Image Analysis
|April 27, 2010
PubMed
Summary

A novel object-based method accurately estimates noise in MRI magnitude images, even with background artifacts. This robust approach adapts the Median Absolute Deviation (MAD) estimator for Rician noise, improving image analysis.

More Related Videos

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

Related Experiment Videos

Last Updated: Jun 13, 2026

Troubleshooting and Quality Assurance in Hyperpolarized Xenon Magnetic Resonance Imaging: Tools for High-Quality Image Acquisition
09:55

Troubleshooting and Quality Assurance in Hyperpolarized Xenon Magnetic Resonance Imaging: Tools for High-Quality Image Acquisition

Published on: January 5, 2024

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

Area of Science:

  • Medical Imaging
  • Signal Processing
  • Image Analysis

Background:

  • Accurate noise estimation is crucial for Magnetic Resonance Imaging (MRI) analysis.
  • Existing methods struggle with background artifacts like ghosting in magnitude MR images.
  • Rician noise is a common characteristic of MR images.

Purpose of the Study:

  • To propose a new object-based method for robust noise estimation in magnitude MR images.
  • To adapt the Median Absolute Deviation (MAD) estimator for Rician noise in the wavelet domain.
  • To evaluate the proposed method's performance against state-of-the-art techniques and assess its impact on denoising.

Main Methods:

  • An object-based approach utilizing wavelet coefficients corresponding to the object.
  • Adaptation of the Median Absolute Deviation (MAD) estimator for Rician noise.
  • An iterative correction scheme based on the image Signal-to-Noise Ratio (SNR).
  • Quantitative validation using synthetic phantoms and a novel framework for real data.

Main Results:

  • The proposed method demonstrates high accuracy and robustness in noise estimation on synthetic images, even with artifacts.
  • Validation on real data shows competitive performance compared to existing methods.
  • The accuracy of noise estimation significantly impacts the performance of denoising filters.

Conclusions:

  • The developed object-based method offers a robust and accurate solution for noise estimation in magnitude MR images.
  • The technique effectively handles background artifacts, outperforming traditional methods.
  • This advancement has implications for improving the quality and reliability of MRI-based image analysis and processing.