Related Experiment Video
Updated: Jun 13, 2026

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
Published on: May 30, 2017
Molecular basis of cholera blood-group dependence and implications for a world characterized by climate change
Asa Holmner1, Alasdair Mackenzie, Ute Krengel
1Department of Biomedical Engineering and Informatics, Västerbotten County Council, Umeå, Sweden.
Abstract:
Climate change has the potential to increase the threat of water-borne diseases, through rises in temperature and sea-level, and precipitation variability. Cholera poses a particular threat, and the need to develop better intervention tools is imminent. Cholera infections are particularly severe for blood group O individuals, who are less protected by the current vaccines. Here we derive a hypothesis as to the molecular origins of blood-group dependence of this disease, based on relevant epidemiological, clinical and molecular data, and give suggestions on how to plan prevention strategies, and develop novel and improved pharmaceuticals.
Related Concept Videos
Cholera
Malaria
Microbes and Climate Change
Determinants of Bacterial Pathogenicity and Virulence
Bacterial Gastroenteritis
What is Climate?

