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Related Concept Videos

Menses Phase01:18

Menses Phase

The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Secretory Phase01:19

Secretory Phase

The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
The Menstrual Cycle01:19

The Menstrual Cycle

The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a uterine...

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Related Experiment Video

Updated: Jun 13, 2026

Improved Hysteroscopic Resection of Endometrial Polyps Using 6-Fr Micro-Scissors and Forceps
03:01

Improved Hysteroscopic Resection of Endometrial Polyps Using 6-Fr Micro-Scissors and Forceps

Published on: August 2, 2024

Pressure-controlled hysteroscopy during menstruation.

Ray Garry1

  • 1University of Western Australia, Perth, Western Australia. raygarry@btinternet.com

Journal of Minimally Invasive Gynecology
|April 27, 2010
PubMed
Summary
This summary is machine-generated.

Hysteroscopy reveals that menstrual shedding and regeneration is a piecemeal process. Adjacent endometrial areas show concurrent shedding and regeneration over several days during the menstrual cycle.

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Area of Science:

  • Reproductive biology
  • Gynecology
  • Endometrial physiology

Background:

  • The menstrual cycle involves complex endometrial changes.
  • Understanding endometrial shedding and regeneration is crucial for reproductive health.

Purpose of the Study:

  • To document the hysteroscopic appearance of the endometrium during menstrual shedding and regeneration.
  • To visualize the dynamic processes of endometrial breakdown and repair.

Main Methods:

  • Prospective observational study conducted at a university hospital.
  • Utilized twin-channel continuous flow hysteroscopy with controlled intrauterine pressure.
  • Included fourteen women with regular menstrual cycles, without recent hormonal therapy.

Main Results:

  • Pressure-controlled hysteroscopy provided clear visualization of the endometrium during the menstrual bleeding phase.
  • Menstruation is characterized by piecemeal shedding and simultaneous regeneration in adjacent endometrial zones.
  • Observed subepithelial hemorrhage, epithelial splitting, and the exposure of glandular and vascular elements.

Conclusions:

  • Pressure-controlled hysteroscopy is effective for visualizing endometrial shedding and regeneration.
  • The process of menstruation is piecemeal, with concurrent shedding and regeneration occurring over multiple days.