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Updated: Jun 13, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
Tibial segmental bone defect reconstruction by Ilizarov type bone transport in an induced membrane
A-P Uzel1, F Lemonne, V Casoli
1Orthopedics and Traumatology Department, Pointe-à-Pitre Regional Teaching Hospital, route de Chauvel, 97159 Pointe-à-Pitre cedex, Guadeloupe. uzel@wanadoo.fr
Abstract:
The management of combined loss of skin coverage and bone substance in the lower third of the leg is problematic. A recommended sequential strategy associates removal of infected tissue and coverage followed by treatment of the bone defect. We report a technique without microsurgery, using Masquelet's induced membrane technique to manage the bone loss, associated to bone transport and coverage by a fasciocutaneous flap with distal pedicle. In a patient presenting with a 10 cm defect with bone exposure, this 2-step procedure allowed consolidation at 7 months without functional sequelae; the fixator was kept in place for 9 months. Neither microsurgery nor cancellous bone graft was required. Using a spacer to induce a membrane facilitated bone transport and distal consolidation.