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Updated: Jun 13, 2026

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
Muscle damaging exercise affects isometric force fluctuation as well as intraindividual variability of cognitive
Albertas Skurvydas1, Marius Brazaitis, Sigitas Kamandulis
1Laboratory of Human Motorics, Department of Applied Physiology and Physiotherapy, Lithuanian Academy of Physical Education, Kaunas, Lithuania. a.skurvydas@lkka.lt
Abstract:
Healthy untrained men (N = 11) were asked to perform 10 series of 12 repetitions of knee eccentric extension (EE) at 160 degrees per second. Quadriceps muscle torques evoked by electrical stimulation at 20 Hz (P20) and 100 Hz (P100), maximal voluntary isometric contraction torque (MVC), maximal isokinetic concentric torque (IT) at 30 degrees per second, voluntary activation index (VA), simple reaction time (RTs), complex reaction time (RTc), and torque variability at 30% of MVC were measured before EE, immediately after EE, and 60 min and 24 hr after EE. MVC, IT, P20, P100, and VA decreased significantly after EE and remained depressed 24 hr later. Torque variability increased significantly after EE. Average RTs and RTc did not change after EE, whereas intraindividual variability in RTs and RTc increased significantly after EE.
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