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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
Theoretical aspects of palladium-catalysed carbon-carbon cross-coupling reactions
1Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
Abstract:
Palladium-catalysed processes for the formation of carbon-carbon bonds, i.e., coupling reactions of organic halides (R(1)X) and main-group organometallic compounds (R(2)M) are most frequently applied in synthesizing biologically and pharmaceutically important organic molecules. In this article, we provide a critical review on theoretical studies of the palladium-catalysed carbon-carbon cross-coupling reactions, and give an up-to-date summary of the current understanding of the cross-coupling reactions from a theoretical point of view (108 references).
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