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Updated: Jun 13, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
[Activity of free radical oxidation and antioxidative system in peripheral blood lymphocytes of patients with
Abstract:
The aim of this work was to evaluate selected parameters of oxidative metabolism in peripheral blood lymphocytes of patients with autoimmune thyroiditis (AIT) at the stages of eu- and hypothyroidism. The lymphocytes were shown to accumulate superoxide anion radical, hydrogen peroxide, and TBA-active products in association with the decrease of major enzymatic activities (superoxide dismutase and catalase). Changes in free radical oxidation and activity of key antioxidative enzymes in AIT patients proved unidirectional.
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